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From: Webster's Revised Unabridged Dictionary (1913)

 Bru·no·ni·an a. Pertaining to, or invented by, Brown; -- a term applied to a system of medicine promulgated in the 18th century by John Brown, of Scotland, the fundamental doctrine of which was, that life is a state of excitation produced by the normal action of external agents upon the body, and that disease consists in excess or deficiency of excitation.